The objectives of this research are: to establish the descriptive profile of the presence of the symptoms of academic stress in high school students, and to determine the relation between the symptoms of stress and the variable sex in the students of upper secondary education. To achieve these objectives, a correlational, transectional and non-experimental study was carried out through the application of the Stress Symptom Inventory, Version Two (SSI-VD) to a sample of 223 students of Escuela Preparatoria Diurna of Universidad Juarez del Estado de Durango. The results indicate that the most frequent symptoms are: "Excessive concern", "Hard to concentrate" and "Restlessness and nervousness". While those that occur less frequently are: "Heart palpitations", "Difficulty to swallow or breath," "Smoking a lot," and "Nervous tics"; on the other hand the correlation analysis indicates that the variable, sex influences in the symptoms of stress, being the women that present them with a greater frequency.