Background: Stress is a common feature in all our lives. It is often seen as a Negative emotion by stress plays on important role in the survival. It helps to face threats and dangerous situations, makes the individual to get motivated and an even make the perform once better. Stress is a state of physical minds for adjustments up on the individual. Stress in nurses are working in intensive care units. The stressing agents and symptoms associated to the Nurses perception of stress, and to assess the correlation between the occurrence of stress, associated to specific situations, such as problems with co-workers, ambiguity and function conflicts,. The work-home double shifts, pressure from superiors according to the individuals perception and changes undergone within the context of the occupation. These situations may be important sources of stress among intensive care nurses was not example from the consequences of intensive care unit stress, showing problems such as dysfunction with work burnout syndrome and observation. Objectives: 1.To assess the stress levels among staff nurses working in intensive care unit. NMCH Nellore. 2.To evaluate the effectiveness of laughter therapy on stress levels among ICU staff nurses 3.To find out the association between the stress level among ICU staff nurses with their selected socio demographic variables. Materials and Methods: The Quasi experimental research design with Simple random sampling technique, 30 staff nurses working in intensive care unit in Narayana Medical College Hospital, Nellore. Results: The result shows that among 60 samples shows that with regard to ICU staff nurses 24(30%) are mild stress, 6(20%) are Moderate stress.