This study aims to examine the relationship between independent variables: Organizational Culture, Transformational Leadership, and Interpersonal Communication with the dependent variable of Job Satisfaction. Proportional random sampling was taken as many as 205 teachers in private madrasah in West Lampung district while testing hypotheses at a significance level of 0.05. The research used a combination of quantitative and qualitative research with the sequential explanatory design. Regression analysis was used to analyze the data. This study concludes that there is a significant and positive relationship between the independent variables of Organizational Culture, Leadership and Interpersonal Communication with Teachers, Job Satisfaction.