Background: The prevalence of anemia in Indonesia is highest in women of childbearing age between the ages of 15-24 years, as many 84.6%. The most common causes of anemia are iron deficiency, resulting from prolonged lack of iron, inadequate intake or absorption of iron, increased need for iron during pregnancy or growth, and increased iron loss as a result of menstruation and intestinal worms. Giving tablets added blood to girls is 76.2%, but those who consume blood-added tablets are only 1.4% due to side effects experienced after consuming these added tablets. Kidney beans are legumes that have complete nutritional content. Flavonoids in kidney beans function for treatment in anemia can work together with iron to ward off free radicals in the form of hydroxy and superoxide so that it protects membrane lipids, prevents cell damage, and protects blood cells. Objective: To determine the effect of red bean powder on the blood profile of white rats (Rattus norvegicus). Method: This research is Quasy experiment with pre-posttest design with control group design. The number of samples in this study were 35 rats divided into 5 groups. The research instrument used a hematology analyzer, preparations, and microscopes. Results: There was an effect of instant red bean powder on the increase in hemoglobin and reticulocytes with a p value <0.05. Conclusion: Giving red bean powder is very influential in increasing hemoglobin and reticulocyte levels.