Annona squamosa is commonly known as custard apple, has various therapeutic properties. Use of Annona squamosa has been comprehensively recommended to remove toxins from the human body. It also use for the treatment of respiratory tract problem like asthma, allergies, anti-tussive and seasonal cold. Researches on Annona squamosa also reported anti-inflammatory, anti-asthematic, anti-microbial and anaphylatic, analgesic, anti-diarrhoeal, immunomodulatory properties of the plant. Annona squamosa belonging to the family Annonaceae is the best example of it. It is a multipurpose tree with edible fruits. Its fruits are commonly known as custard apple which is eatable. The pulp can be used as flavouring in ice cream. Between 50-80% of the fruit is edible. The Vitamin C content is appreciable (35-42 mg/100 g) and slightly higher than in grapefruit. The nutrient value of thiamine, potassium and dietary fiber is also significant. It is reported to contain various chemical compounds such as alkaloid, isomeric hydroxyl ketones from leaf, acetogenin, samaquasine, annonacin and annonastatin from seeds, acetogenin, squamone from bark of it. Various studies have been reported as an antibacterial, antidiabetic, antitumor, anti-malarial, anthelmintic, anti-genotoxic potential and hepatoprotective activity. The leaves are used as a vermicide, for treating cancerous tumors, also applied to abscesses, insect bites and other skin complaints. The crushed leaves were sniffed to overcome the hysteria and fainting spells, and they were also applied on the ulcers and wounds.”