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VOL. 6, ISSUE 4 (2021)
Differential gene expression analysis by single cell RNA sequencing reveals insight to genetic diseases
Authors
Sudheer Menon
Abstract
World’s population is increasing at a highest rate ever in the history. In the past people lived a very short lifespan due to prevailed diseases. Now a days, people are enjoying modern health facilities and living a long life. It has become possible due to the services of science for mankind. Single cell RNA sequencing has led us to revolutionize the field of medicine by making it possible to study the role of genetic expression in causing different diseases. Gene expression has unveiled the possible causes of genetic and infectious diseases. The prime objective of the study was to devise new ways and methods to explicit the role of gene expression to reveal the insights of several genetic diseases. Total 12 rats were used as model organism and were reared under laboratory conditions. Rats were slaughtered and cell culture was obtained. Laser Capture Microdissection was used to extract single cell from cell culture. 6 pieces of 12 micrometer size were obtained and further processed to study the gene expression. The results showed that there was a significant involvement of genes expression in causing genetic diseases like cancer, phenylketonuria, sickle cell anemia and.
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Pages:1-7
How to cite this article:
Sudheer Menon "Differential gene expression analysis by single cell RNA sequencing reveals insight to genetic diseases ". International Journal of Multidisciplinary Education and Research, Vol 6, Issue 4, 2021, Pages 1-7
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