Even at the intellectual level, the categories of politics, religion, and ethnicity pose difficulties. The interconnectedness of politics, religion, and ethnicity as social dynamics in promoting the growth of a nation, however, has become crucial everywhere in the world. Nigeria is a multi-ethnic country with cultural diversity among its ethnic groupings. Political upheaval, ethnic chauvinism, young restlessness, corruption, religious prejudice and extremism, as well as other social vices that impede national progress, have plagued the country. In light of the foregoing, this study explores how politics, religion, and ethnicity have an impact on Nigeria's national growth. Cross-sectional data were gathered using a structured questionnaire across the twenty-five local government areas of Delta State using a descriptive methodology. 400 respondents were polled using a questionnaire using non-probabilistic sample strategies, including convenient and purposeful methods. Correlation and regression analyses were performed on the data that were collected. The study's conclusions demonstrated that politics, religion, and ethnicity had a detrimental and considerable impact on Nigeria's national growth. Based on these findings, the study makes several recommendations, including that the country needs a focused leadership that has a vision for how to put its citizens at the center of the political project without resorting to ethnic chauvinism and sees obtaining political power as a means of promoting the welfare of its people as a whole, regardless of their ethnic origin.