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VOL. 8, ISSUE 4 (2023)
Efficacy of Glycyrrhiza glabra as an antibacterial agent against isolates that produce biofilm and beta-lactamases
Authors
S Sivanantham, N Thangaraj, B Indhu, C Jayalakshmi
Abstract
When it comes to human relationships with the
natural world, the use of herbal remedies in Asia symbolizes a long history.
Antibiotic resistance has emerged as a primary therapeutic dilemma around the
globe in recent years, in addition to the rise in the number of diseases. It is
common knowledge that plants are a source of active metabolites; hence, they
serve as the foundation for a wide variety of pharmacological products. In
addition to having anti-inflammatory and expectorant characteristics, Glycyrrhiza
glabra is a highly pleasant, moist, and soothing plant. It also has the
ability to reduce coughing and has hormonal effects. Individuals of Staphylococcus
aureus and Klebsiella pneumonia that have developed resistance to
multiple drugs. Ethanol extract was used for the GC-MS analysis of these three
different extracts. In the ethanol extract, tannins, saponins, phenols, and
terpenoids were found. Proteins were not present in either of the extracts. The
ethanol extract had the maximum amount of phytochemicals compared to the
chloroform extract. An advantageous component was found in Glycyrrhiza
glabra, and it demonstrated antibacterial action against clinical isolates
that produced beta-lactamases. Therefore, it has the potential to be utilized
as an antibacterial agent against a wide variety of microbes, which is superior
to the usage of traditional antibiotics.
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Pages:81-86
How to cite this article:
S Sivanantham, N Thangaraj, B Indhu, C Jayalakshmi "Efficacy of <i>Glycyrrhiza glabra</i> as an antibacterial agent against isolates that produce biofilm and beta-lactamases". International Journal of Multidisciplinary Education and Research, Vol 8, Issue 4, 2023, Pages 81-86
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